Immunosuppressive treatment for idiopathic membranous nephropathy in adults with nephrotic syndrome

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Immunosuppressive Treatment for Nephrotic Idiopathic Membranous Nephropathy: A Meta-Analysis Based on Chinese Adults

BACKGROUND Idiopathic membranous nephropathy (IMN) is the most common pathological type for nephrotic syndrome in adults in western countries and China. The benefits and harms of immunosuppressive treatment in IMN remain controversial. OBJECTIVES To assess the efficacy and safety of different immunosuppressive agents in the treatment of nephrotic syndrome caused by IMN. METHODS PubMed, EMBA...

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Spontaneous remission of nephrotic syndrome in idiopathic membranous nephropathy.

Spontaneous remission is a well known characteristic of idiopathic membranous nephropathy, but contemporary studies describing predictors of remission and long-term outcomes are lacking. We conducted a retrospective, multicenter cohort study of 328 patients with nephrotic syndrome resulting from idiopathic membranous nephropathy that initially received conservative therapy. Spontaneous remissio...

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Horseshoe kidney and nephrotic syndrome due to idiopathic membranous nephropathy.

Urinary tract infection, hydronephrosis, calculi, and tumor of the renal pelvis are knownas complications and multiple congenital anomalies can occur together with a horseshoe kidney (1). However, the occurrence of membranousnephropathy (MN) in a horseshoe kidney has been only reported in a few case reports (2, 3). Furthermore, horseshoe kidney and focal sclerosing glomerulonephritis were seen ...

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20 years after methylprednisolone/chlorambucil treatment in idiopathic membranous nephropathy stage II-III with nephrotic syndrome.

There is now controlled evidence that a 6-month course with methylprednisolone and chlorambucil may favour remission of the nephrotic syndrome and may significantly improve the 10-year kidney survival in patients with idiopathic membranous nephropathy. We analyzed the outcome of 15 nephrotic patients (proteinuria 7.06 +/- 1.07 g/d), stage II-III membranous nephropathy, aged 37.93 +/- 2.32, 8 ma...

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Treatment with rituximab in idiopathic membranous nephropathy

BACKGROUND Rituximab represents a valid therapeutic option to induce remission in patients with primary glomerulonephritis. Despite several studies proving its efficacy in improving outcomes in patients with membranous nephropathy (MN), its role in therapeutic protocols is not yet defined. METHODS We studied 38 patients with idiopathic MN treated with rituximab (in 13 patients as first-line t...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2014

ISSN: 1465-1858

DOI: 10.1002/14651858.cd004293.pub3